Antimicrobial screening of the crude extract of Hannoa klaineana against some pathogens
DOI:
https://doi.org/10.30574/gscbps.2020.12.1.0233Keywords:
Antimicrobial, Phytochemical, Bacteria, Fungi, Hannoa klaineana.Abstract
Hannoa klaineana is an ever green plant belonging to the Simaroubaceae family commonly known as Oghuru in Igbo, itekiri in Edo and igi gun in Yoruba. It has been used in ethnomedicine for the treatment of malaria, cough, and stomach problems. The present study assessed the antimicrobial property of the extract of H. klaineana against Staphylococcus aureus, Salmonella typhi, Escherichia coli, Pseudomonas aeruginosa, Bacilus substilus, and Candida albicans using the agar diffusion method. Our preliminary phytochemical studies showed the presence of resins, steroids, terpenoids, glycosides, alkaloids, flavonoids, tannins, saponins, and phenols. Quantitative determination of the phytochemicals present revealed alkaloids (1.2%), tannins (11.2%), flavonoids (3%), saponins (29.3%), and phenolic compounds (45.7%). The extract of H. klaineana showed good antimicrobial activity against C. albicans and moderate active against S. aureus, S. typhi, E. coli, P. aeruginosa, B. substilus. These results further confirm the potentials of Nigerian plants as a source of bioactive compounds with pharmaceutical, agricultural or industrial applications.
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References
World Health Organization. (2004). Medicinal plants - guidelines to promote patient safety and plant conservation for a U$ 60 billion industry.
Ernst E. (2005). The efficacy of herbal medicine: An overview. Fundam Clin Pharmacol, 19(4), 405-09.
Aiyeloja AA and Bello OA. (2006). Ethnobotanical potentials of common herbs in Nigeria: A case study of Enugu state. Educational Research and Reviews, 1(1), 16–22.
Oteng-Amoako AA. (2006). 100 tropical African timber trees from Ghana: tree description and wood identification with notes on distribution, ecology, silviculture, ethnobotany and wood uses. Candara and CG Omega, Ghana.
Francois G, Diakanamwa C and Timperman G. (1998). Antimalaria and cytotoxic potential of four quassinoids from Hannoa chlorantha and Hannoa kleineana and their structure activity relationships. International Journal for parasitology, 28(4), 635-40.
Ajaegbu EE, Younossa L, Danga Yinyang PS, Uzochukwu CI and Okoye Festus BC. (2016). Mosquito repellent activity of Spondias mombin L. (Family Anacardiaceae) crude methanol extract and fractions against Aedes aegypti (L.). IJNPR, 7(3), 240-44.
Trease GE and Evans WC. (1989). Pharmacognosy, 13th Edition. Baillere Tindall, London, 39-250.
Edeoga HO, Okwu DE and Mbaebie BO. (2005). Phytochemical Constituents of some Nigerian Medicinal Plants. African Journal of Biotechnology, 4(7), 685-88.
Harborne JB. (1973). Phytochemical methods. A guide to Modern Technique of Plant Analysis. Chapman and Hall, LTD. London, 1-389.
Boham BA and Kocipai-Abyazan R. (1974). Flavonoids and Condensed tannins from leaves of Hawaiian V. aticulatum and V. calycinium. Pacific Science, 48, 458 – 63.
Obdoni BO and Ochuko PO. (2008). Phytochemical studies and comparative efficacy of crude extracts of some homostatic plants in Edo and Delta States of Nigeria. Global Journal of Pure Applied Sciences, 203 – 208.
Anchama C, Aphiwat T and Nuansiri R. (2005). Screening of antioxidant activity and antioxidant compounds of some edible plants of Thailand. Food Chemistry, 93, 491 – 497.
Okeke MI, Iroegbu CU, Eze EN, Okoli AS and Esimone CO. (2001). Evaluation of extracts of the root of Landolphiaowerrience for antibacterial activity. J Ethnopharmacol, 78, 119-127.
Odeghe OB, Monanu MO and Anacletus FC. (2016). Phytochemistry of Achomanes Difformis Stem, Dioscorea Bulbifera Stem Bark, Fadogia Cienkowskii Leaf, Hannoa Klaineana Stem and Vitex Simplicifolia Leaf. Advances in Multidiscipline and Scientific Research, 2(1).
Danijela P, Barbara S, Ivana S, Slavica D, Josipa B, Gordana R, Katlego E and Jacobus N. Phenolic Composition of Leaf extracts of Ailanthus altissima (Simaroubaceae) with Antibacterial and Antifungal Activity Equivalent to Standard Antibiotic. Natural Product Communications, 12(10), 1609 -12.
Ajaiyeoba EO and Krebs HC. (2003). Antibacteria and antifungal activities of Quassia undulate and Quassia amara extracts in vitro. African Journal of Medicine and Medical Sciences, 32(4), 353-56.
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