Prospective designing and types of buccal drug delivery system: The Review

Surajkumar Bhaskarao Rathod; Nilesh Prakashrao Tekade; Dr. Nitin Shridharao Bhajipale; Dr. Dhirendra Babji Sanghai

doi:10.30574/gscbps.2020.12.3.0298

Authors

Surajkumar Bhaskarao Rathod Student of Master of Pharmacy, department of Pharmaceutics, S.G.S.P.S. Institute of Pharmacy, Khulkhed, Akola, (MH), India.444002.
Nilesh Prakashrao Tekade Faculty in department of Pharmaceutics, S.G.S.P.S. Institute of Pharmacy, Khulkhed, Akola, (MH), India.444002.
Dr. Nitin Shridharao Bhajipale Principal, S.G.S.P.S. Institute of Pharmacy, Khulkhed, Akola, (MH), India.444002.
Dr. Dhirendra Babji Sanghai Faculty in department of Pharmaceutics, S.G.S.P.S. Institute of Pharmacy, Khulkhed, Akola, (MH), India.444002.

DOI:

https://doi.org/10.30574/gscbps.2020.12.3.0298

Keywords:

Bioadhesive film, Bioavailability, Buccal patches

Abstract

Buccal bioadhesive films, releasing topical drugs in the oral cavity at a slow and predetermined rate, provide distinct advantages over traditional dosage forms for treatment of many diseases. The mucosa of the buccal cavity is the most easily accessible transmucosal site. This fast dissolving drug delivery system (FDDS) is suited for the drugs which undergo high first pass metabolism and is used for improving bioavailability with reducing dosing frequency to mouth plasma peak levels, which in turn minimize adverse/side effects and also make it cost effective This article aims to review the recent Designs of buccal patches and their developments in the buccal adhesive drug delivery systems, & Buccal drug delivery is a promising area for continued research with the aim of systemic delivery of orally inefficient drugs as well as a feasible and attractive alternative for non-invasive delivery of potent peptide and protein drug molecules.

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