Blood donation type and hepatitis B and C seroepidemiology at Hôpital Sominé DOLO de Mopti
DOI:
https://doi.org/10.30574/gscbps.2020.13.3.0393Keywords:
Blood donation, Hepatitis, Seroepidemiology, Hôpital Sominé DOLO de Mopti.Abstract
Background: The increasing prevalence of hepatitis viral markers in developing countries results in a concern in the setting of blood transfusion safety. The aim of this study was to assess the prevalence of hepatitis viral markers among blood donors and their link with sociodemographic factors.
Methods: We performed a retrospective study on blood donors screened for HBV and HCV. HBV and HCV serologies were performed by immunochromatographic methods using Alere DetermineTM HBs-Ag and SD BIOLOLINETM HCV-Ab. Data were analyzed by R 3.4.3. The logistic regression was fitted in univariate and multivariate analysis.
Results: A total of 11.372 donors were enrolled. The overall prevalence was 10.4%. The specific prevalence of HBV and HCV were 8.9% and 1.5% respectively. The co-infection rate was 0.3%. HBV seropositivity proportion was significantly higher in family donors compared to volunteer (9,8% vs 6,0%, or = 1.71 [1.30-2.29] p < 0,001). HBV seropositivity was positively influenced by male sex aOR = 1,77 [1,4-2,26], p < 0.001 and unemployed aOR = 1.20 [1.03-1.40], p = 0.02 in multivariate analysis.
Conclusion: Our data suggest that voluntary donors and particularly female which had an occupation had a lower prevalence of hepatitis viral markers.
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