Blood donation type and hepatitis B and C seroepidemiology at Hôpital Sominé DOLO de Mopti

Modibo Coulibaly; Bakary Maiga; Moussa Diawara; Dramane Samaké; Valentin Sagara; Bréhima Traoré; Oumar Guindo; Mounirou Baby; Amagana DOLO

doi:10.30574/gscbps.2020.13.3.0393

Authors

Modibo Coulibaly Centre National de Recherche Scientifique et Technologique, Biomedical laboratory, Hôpital Sominé DOLO de Mopti, Mopti, Mali.
Bakary Maiga Université des Sciences Techniques et Technologiques de Bamako, Faculty of pharmacy, Bamako, Mali.
Moussa Diawara Centre National de Recherche Scientifique et Technologique, Biomedical laboratory, Hôpital Sominé DOLO de Mopti, Mopti, Mali.
Dramane Samaké Centre National de Recherche Scientifique et Technologique, Medicine, Hôpital Sominé DOLO de Mopti, Mopti, Mali.
Valentin Sagara Centre National de Recherche Scientifique et Technologique, Biomedical laboratory, Hôpital Sominé DOLO de Mopti, Mopti, Mali.
Bréhima Traoré Centre National de Recherche Scientifique et Technologique, Public Health, Hôpital Sominé DOLO de Mopti, Mopti, Mali.
Oumar Guindo Centre National de Recherche Scientifique et Technologique, Public Health, Hôpital Sominé DOLO de Mopti, Mopti, Mali.
Mounirou Baby Université des Sciences Techniques et Technologiques de Bamako, Faculty of pharmacy, Bamako, Mali.
Amagana DOLO Université des Sciences Techniques et Technologiques de Bamako, Faculty of pharmacy, Bamako, Mali.

DOI:

https://doi.org/10.30574/gscbps.2020.13.3.0393

Keywords:

Blood donation, Hepatitis, Seroepidemiology, Hôpital Sominé DOLO de Mopti.

Abstract

Background: The increasing prevalence of hepatitis viral markers in developing countries results in a concern in the setting of blood transfusion safety. The aim of this study was to assess the prevalence of hepatitis viral markers among blood donors and their link with sociodemographic factors.

Methods: We performed a retrospective study on blood donors screened for HBV and HCV. HBV and HCV serologies were performed by immunochromatographic methods using Alere Determine^TM HBs-Ag and SD BIOLOLINE^TMHCV-Ab. Data were analyzed by R 3.4.3. The logistic regression was fitted in univariate and multivariate analysis.

Results: A total of 11.372 donors were enrolled. The overall prevalence was 10.4%. The specific prevalence of HBV and HCV were 8.9% and 1.5% respectively. The co-infection rate was 0.3%. HBV seropositivity proportion was significantly higher in family donors compared to volunteer (9,8% vs 6,0%, or = 1.71 [1.30-2.29] p < 0,001). HBV seropositivity was positively influenced by male sex aOR = 1,77 [1,4-2,26], p < 0.001 and unemployed aOR = 1.20 [1.03-1.40], p = 0.02 in multivariate analysis.

Conclusion: Our data suggest that voluntary donors and particularly female which had an occupation had a lower prevalence of hepatitis viral markers.

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