A prospective comparative study to evaluate the effect of Myo-inositol plus diet vs diet alone in patients with gestational diabetes mellitus

B Swathi; A Deepthi; B Sravani; Rekha; S Namratha; R Sandhya

doi:10.30574/gscbps.2021.14.3.0076

Authors

B Swathi Bharat School of pharmacy, Mangalpally, Ibrahimpatnam, Hyderabad-501510, India.
A Deepthi Bharat School of pharmacy, Mangalpally, Ibrahimpatnam, Hyderabad-501510, India.
B Sravani Bharat School of pharmacy, Mangalpally, Ibrahimpatnam, Hyderabad-501510, India.
Rekha Department of obstetrics and gynaecology, Durgabai Deshmukh Hospital and Research Centre, Vidyanagar, Hyderabad, India.
S Namratha Bharat School of pharmacy, Mangalpally, Ibrahimpatnam, Hyderabad-501510, India.
R Sandhya Bharat School of pharmacy, Mangalpally, Ibrahimpatnam, Hyderabad-501510, India.

DOI:

https://doi.org/10.30574/gscbps.2021.14.3.0076

Keywords:

Biological and Pharmaceutical Sciences, Myoinositol, OGTT test, Diet, Insulin

Abstract

Aim: The aim of this study was to compare the effect of Myo-inositol plus diet and diet alone in patients with gestational diabetes mellitus.

Materials and methods: A Randomized Prospective study was carried out in Gestational Diabetes Mellitus patients to evaluate the efficacy of Myoinositol+diet vs Diet alone in the department of Gynaecology, Durgabhai Deshmukh Hospital, a 300 bedded multispecialty hospital from September 2018-April 2019.OGTT test was conducted to measure blood glucose levels.

Results: Among the total number of patients (60), Myoinositol + diet is given in 50% and diet is given in 50% of the patients. Among 30 patients on diet, 19 patients couldn’t control rising blood glucose levels and were prescribed insulin for reduction of blood glucose levels. Among 30 patients on myoinositol+ diet, 4 patients couldn’t control 1 hr blood glucose levels and were prescribed insulin to control blood glucose levels.

Conclusion: This study showed that Myoinositol + diet is effective than only diet with respect to decrease in blood glucose levels and safety among patients with Gestational Diabetes Mellitus. Therefore, we conclude that myoinositol + diet is safe and effective in reducing fasting and 2hr blood glucose levels.

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