Conductometric studies of 1, 3, 5 –triazinothiocarbamide at different concentration and temperature

DD  Sonone; ME  Shelke; DT  Tayade

doi:10.30574/gscbps.2021.16.2.0244

Authors

DD Sonone Department of Chemistry, Government Vidarbha Institute of Science and Humanities, Amravati, Maharashtra, India.
ME Shelke Department of Chemistry, Government Vidarbha Institute of Science and Humanities, Amravati, Maharashtra, India.
DT Tayade Department of Chemistry, Government Vidarbha Institute of Science and Humanities, Amravati, Maharashtra, India.

DOI:

https://doi.org/10.30574/gscbps.2021.16.2.0244

Keywords:

Conductometric measurements, Thermodynamic parameters, Pharmokinetics, Pharmodynamics, S-triazines

Abstract

Conductivity plays vital role in drug diffusion. Thermodynamic parameters affected by substituents of drug. Thermodynamic parameters of 1, 3, 5 –triazinothiocarbamide (1a) have been investigated by using conductometrically carried out at different molar concentrations. This work highlights investigation of G, K and µ values. The thermodynamic parameters viz. ΔH, ΔS and ∆G for ion pair formation determine from the value of ion association constant. This technique is suitable and accurate to study of pharmokinetics and pharmodynamics parameters.

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