Some bioactive component analysis of herbal capsules

Mustafa  Yaşar; Sibel Bayıl  Oğuzkan; Halil İbrahim  Uğraş

doi:10.30574/gscbps.2021.17.2.0271

Authors

Mustafa Yaşar Clinic of Remember RegenerationTherapy Method, İstanbul, Turkey.
Sibel Bayıl Oğuzkan University of Gaziantep, Vocational School of Health, Gaziantep, Turkey.
Halil İbrahim Uğraş University of Düzce, Arts and Science Faculty, Chemistry Department, Düzce, Turkey.

DOI:

https://doi.org/10.30574/gscbps.2021.17.2.0271

Keywords:

DPPH, DNA, Pbr 322, TAL, TOL

Abstract

Since the beginning of the evaluation of plants in terms of human health, the bioactivity properties of plants have been studied in the laboratory and thus standards have been brought to the treatment methods with plants. For this purpose, some bioactive component analyzes of 18 herbal capsules and 2 liquid herbal syrups produced by Naturin Company were performed in our current study. In this context, the total oxidant and antioxidant status of these plant mixtures were evaluated. The free radical capacities of the samples were determined by 1, 1-diphenyl-2-picrylhydrazil (DPPH) method and their DNA protective activities were determined using pBR322 plasmid DNA. Total antioxidant level (TAL) and Total oxidant level (TOL) activities were performed using Rel Assay diagnostic kit. All 3 of the stinging nettle samples showed DNA protective activity. The clean sample containing milk thistle extract also showed DNA Protective activity. In both the syrup samples (My guard and DTX-19) results were detected in the direction of positive protection on DNA. When the DPPH radical scavenging capacity was examined, it was determined that the best results were in juniper, nettle and thistle thistle samples, and the samples with syrup had a very good radical scavenging effect, and all of the samples showed antioxidant activity. This study is a preliminary and supportive study in order to elucidate the properties that can be used as drug active ingredients in traditional medicine, especially in the field of pharmacology.

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