Black phosphorus nanosheet-based new drug delivery system for the anticancer agents: A review

Chaitanya A. Gulhane 1, Adarsh R. Durge 1, Jagdish V. Manwar 2, * and Ravindra L. Bakal 1

1 IBSS’s Dr. Rajendra Gode Institute of Pharmacy, Mardi Road, Amravati-444 602, MS, India.
2 IBSS’s Dr. Rajendra Gode College of Pharmacy, Mardi Road, Amravati-444 602, MS, India.
 
Review Article
GSC Biological and Pharmaceutical Sciences, 2021, 16(02), 014–027.
Article DOI: 10.30574/gscbps.2021.16.2.0214
Publication history: 
Received on 25 June 2021; revised on 05 August 2021; accepted on 07 August 2021
 
Abstract: 
Cancer has been one among the main threats to the lives of citizenry for hundreds of years. Traditional drug therapy has certain defects such as poor targeting, easy degradation, high side effects, etc. Therefore, to enhance the treatment efficiency of anticancer agents, there is need of developing new drug delivery systems.  Black phosphorus is a member of the 2D family, and it possess the potential to construct drug delivery system by virtue of its photothermal therapy, photodynamic therapy, and biodegradable properties. Due to their special structure BP are considered to be the best platform for drug delivery. They have shown large potential as near-infrared photothermal therapy agents and drug delivery for cancer therapy. The present review covered advances in BP- based drug delivery system along with its advantages and applications in cancer therapy.
 
Keywords: 
Black phosphorus; Photothermal therapy; Photodynamic therapy; Nanomaterials.
 
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