A review on micro beads: Formulation, technological aspects, and extraction

Shaik Khaja Moinuddin 1, Pradeep Kumar M 1, *, Sandeep Kumar G 2, Perugumi Ramya 3, Konda Sravya Sree 3 and Kavya K 4

1 Department of Pharmaceutics, Vasavi Institute of Pharmaceutical Sciences, Vasavi Nagar, Peddapalli (V), Sidhout (M), YSR Kadapa-516 247, Andhra Pradesh, India.
2 Department of Pharmaceutics, St. Peter's Institute of Pharmaceutical Sciences, Vidya Nagar, Hanamkonda, Telangana 506001, India.
3 Ratnam Institute of Pharmacy, Pidathapolur Village and Post, Muthukur (M), SPSR Nellore, Andhra Pradesh 524346, India.
4 V. V. Institute of Pharmaceutical Sciences, Gudlavalleru – 521356, Krishna District, Andhra Pradesh, India.
 
GSC Biological and Pharmaceutical Sciences, 2024, 26(02), 059–066.
Article DOI: 10.30574/gscbps.2024.26.2.0043
Publication history: 
Received on 23 December 2023; revised on 02 February 2024; accepted on 05 February 2024\
 
Abstract: 
Any drug delivery system's purpose is to deliver a therapeutic amount of medicine to the appropriate place in the body while also achieving and maintaining the correct drug concentration. This could be accomplished by using numerous unit dosage forms such as microgranules/spheroids, pellets, microcapsules, and beads, which are divided into many separate units, referred to as subunits, each of which possesses certain desired features. The advantages of micro particle drug delivery systems over single unit dose form are well documented. One of the solutions that does not entail the use of harsh chemicals or elevated temperatures is the production of microbeads medication delivery systems. The traditional procedures require the use of ionotropic gelation methods, which include internal and external gelation methods, emulsion gelation methods, polyelectrolyte complexation methods, and so on. Because of the ease of preparation, the majority of work has been done on the preparation of microbeads using the ionotropic gelation process rather than alternative approaches.
 
Keywords: 
Microbeads; Formulation; Coventional Techniques; Extraction
 
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