Review on production of citric acid by fermentation technology

Sweta V. Lende 1, *, Heera Karemore 2 and Milind J. Umekar 3

Department of Quality Assurance Smt. Kishoritai Bhoyar College of Pharmacy, Kamptee Rashtrasant Tukadoji Maharaj University, Nagpur Pin-441002.
 
Review Article
GSC Biological and Pharmaceutical Sciences, 2021, 17(03), 085–093.
Article DOI: 10.30574/gscbps.2021.17.3.0313
Publication history: 
Received on 13 October 2021; revised on 05 December 2021; accepted on 07 December 2021
 
Abstract: 
Citric acid is the most important organic acid produced in tonnage and is extensively used in food and pharmaceutical industries. It is produced mainly by submerged fermentation using Aspergillus niger or Candida sp. from different sources of carbohydrates, such as molasses and starch-based media. In view of surges in demand and growing markets, there is always a need for the discovery and development of better production techniques and solutions to improve production yields and the efficiency of product recovery. To support the enormous scale of production, it is necessary and important for the production process to be environmentally friendly by utilizing readily available and inexpensive agro-industrial waste products, while maintaining high production yields. This review article for fermentation of citric acid and Microbial production of citric acid, Substrates and strategies of citric acid production for Surface fermentation, Submerged fermentation, Solid-state fermentation and also the effects of various Factors affecting of citric acid fermentation conditions are Carbon source, Nitrogen limitation, Phosphorus source, Lower Alcohols, pH of culture medium, Trace elements, Aeration and Other factors. citric acid recovery options and the numerous applications of citric acid, based on the literature review information of citric acid production by fermentation technology.
 
Keywords: 
Review; citric acid production; fermentation technology; Factors effect on fermentation.
 
Full text article in PDF: 
Share this