Bilayer tablet technology: A novel approach

Venkateswara Rao Sadhu; Priyanka Bopparaju; Padmalatha Kantamneni

doi:10.30574/gscbps.2019.7.2.0033

Authors

Venkateswara Rao Sadhu Department of Pharmaceutics, Vijaya Institute of Pharmaceutical Sciences for Women, Enikepadu, Vijayawada–521108, India.
Priyanka Bopparaju Department of Pharmaceutics, Vijaya Institute of Pharmaceutical Sciences for Women, Enikepadu, Vijayawada–521108, India.
Padmalatha Kantamneni Department of Pharmacology, Vijaya Institute of Pharmaceutical Sciences for Women, Enikepadu, Vijayawada–521108, India.

DOI:

https://doi.org/10.30574/gscbps.2019.7.2.0033

Keywords:

Bilayer tablet, Sustained release, Immediate release, Incompatible

Abstract

Bilayer tablet is new era for the successful development of controlled release formulation along with various features to provide a way of successful drug delivery system. Controlled release dosage forms have been extensively used to improve therapy with several important drugs. Use of bilayer tablet is a very different aspect for anti-inflammatory and analgesic. Bilayer tablet is suitable for sequential release of two drugs in combination, separate two incompatible substances and also for sustained release tablet in which one Layer is immediate release as initial dose and second layer is maintenance dose. Bilayer tablet is improved beneficial technology to overcome the shortcoming of the single layered tablet. This article provides an overview of the bilayer tablet technology, highlighting the main benefits of this type of oral dosage forms while providing a description of current challenges and advances toward improving manufacturing practices and product quality.

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