Role of antibody diversity in the management of malaria parasite invasion

Ebunoluwa A Excelence; J. Muhammad Farouk; M. Musa Munir; E. Chime Ogbodo; Godwin E Shaibu; K. Abdulazeez Adeniyi

doi:10.30574/gscbps.2019.9.1.0167

Authors

Ebunoluwa A Excelence Department of Biochemistry, Federal University of Technology, Minna PMB 65, Minna, Nigeria.
J. Muhammad Farouk Department of Biochemistry, Federal University of Technology, Minna PMB 65, Minna, Nigeria.
M. Musa Munir Department of Biochemistry, Federal University of Technology, Minna PMB 65, Minna, Nigeria.
E. Chime Ogbodo Department of Biochemistry, Federal University of Technology, Minna PMB 65, Minna, Nigeria.
Godwin E Shaibu Department of Biochemistry, Federal University of Technology, Minna PMB 65, Minna, Nigeria.
K. Abdulazeez Adeniyi Department of Animal Biology Federal University of Technology, Minna PMB 65, Minna, Nigeria.

DOI:

https://doi.org/10.30574/gscbps.2019.9.1.0167

Keywords:

Malaria, Antibody, Plasmodium, Immune response

Abstract

The widespread incidence of malaria infection which result in breakdown of immunity and consequently death in the absence of effective health care measures such administration of appropriate drugs is as a result of failure of the immune system in combating the pathogenic Plasmodium species responsible for malaria infection. This review focuses on the role of antibodies in immune response to malaria and the role of antibody variation in the management of malaria.

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References

World Health Organization. (2019). International Travel and Health: Malaria.

Lawal B, Shittu OK, Abubakar A and Kabiru AY. (2018). Human Genetic Markers and Structural Prediction of Plasmodium Falciparum Multi-Drug Resistance Gene (Pfmdr1) For Ligand Binding in Pregnant Women Attending General Hospital Minna. Journal of Environmental and public health, Volume 2018, 1-13.

Anthony PC and Lennox A. (2017). Infectious Diseases: Plasmodium species (Malaria). Infectious Disease Advisor.

Lawal B, Shittu OK, Kabiru AY, Jigam AA, Umar MB, Berinyuy EB and Alozieuwa BU. (2015). Potential antimalarials from African natural products: A review. Journal of Intercultural Ethnopharmacology, 4(4), 318-343.

Deitsch KW and Hviid L. (2004). Variant Surface Antigens, Virulence Genes and the Pathogenesis of Malaria. Trends In Parasitology, 20(12), 562–566.

WHO, World Malaria Report. (2016). World Health Organization, Geneva.

Hisaeda H, Yasutomo K and Himeno K. (2005). Malaria: Immune Evasion by Parasites. The International Journal of Biochemistry and Cell Biology, 37(4), 700-706.

Pertea M and Salzberg SL. (2010). Between a Chicken and a Grape: Estimating the Number of Human Genes. Genome Biology, 11(5), 206.

Stein LD. (2004). Human genome: End of the beginning. Nature, 431(7011), 915-916.

Rhoades RA and Pflanzer RG. (2002). Human Physiology (4th ed.). Thomson Learning. 584.

Janeway C. (2001). Immunobiology (5th ed.). Garland Publishing.

Litman GW, Rast JP, Shamblott MJ, Haire RN, Hulst M, Roess W, et al. (1993). Phylogenetic Diversification of Immunoglobulin genes and the Antibody Repertoire. Molecular Biology and Evolution, 10 (1), 60–72.

Sinnis P and Zavala F. (2012). The Skin: Where Malaria Infection and the Host Immune Response Begin. Seminars in Immunopathology, 34(6), 787–792.

Rénia L and Goh YS. (2016). Malaria Parasites: The Great Escape. Frontiers in Immunology, 7, 463.

Gomes PS, Bhardwaj J, Rivera-Correa, JC, Freire-De-Lima G and Morrot A. (2016). Immune Escape Strategies of Malaria Parasites. Frontiers in Microbiology, 7, article 1617.

Dinko B and Pradel G. (2016). Immune Evasion by Plasmodium Falciparum Parasites: Converting a Host Protection Mechanism for The Parasite’s Benefit. Advances in Infectious Diseases, 6, 2, article 67759.

Dennison NJ, BenMarzouk-Hidalgo OJ and Dimopoulos G. (2015). Micro RNA-regulation of Anopheles Gambiae Immunity to Plasmodium Falciparum Infection and Midgut Microbiota. Developmental & Comparative Immunology, 49(1), 170–178.

Murphy K. (2012). Janeway's Immunobiology. 8th ed. Vol. 19, New York: Garland Science, 868.

Dennis KF. (2012). Antibody Diversity.In: Immunology for Pharmacy, 79-86.

Sagar A. (2018). Antibody Structure, Classes and Functions.

Artavanis-Tsakonas K, Tongren JE and Riley EM. (2003). The War Between the Malaria Parasite and the Immune System: Immunity, Immunoregulation and Immunopathology. Clinical and Experimental Immunology, 133(2), 145–152.

Guilbride DL, Guilbride PL and Gawlinski, P. (2012). Malarias Deadly Secret: A Skin Stage. Trends in Parasitology, 28(4), 142150