A rare case of metastasis from primitive breast cancer in endometrioid adenocarcinoma

Stefania Erra; Alessia Frigeri; Luca Michele De; Luca Zambello; Valentina  Caminiti; Roberta Buosi

doi:10.30574/gscbps.2020.11.3.0190

Authors

Stefania Erra Surgical Pathology Department, Santo Spirito Hospital, Casale Monferrato, Viale Giolitti 2, Italy
Alessia Frigeri Surgical Pathology Department, Santo Spirito Hospital, Casale Monferrato, Viale Giolitti 2, Italy
Luca Michele De Surgical Pathology Department, Santo Spirito Hospital, Casale Monferrato, Viale Giolitti 2, Italy
Luca Zambello Surgical Pathology Department, Santo Spirito Hospital, Casale Monferrato, Viale Giolitti 2, Italy
Valentina Caminiti Surgical Pathology Department, Santo Spirito Hospital, Casale Monferrato, Viale Giolitti 2, Italy
Roberta Buosi Oncology Unit, Santo Spirito Hospital, Casale Monferrato, Viale Giolitti 2, Italy.

DOI:

https://doi.org/10.30574/gscbps.2020.11.3.0190

Keywords:

Primitive breast cancer, Endometrial adenocarcinoma, Infiltrating ductal carcinoma

Abstract

Breast cancer is the most common cancer in women, with a high mortality rate. Genital metastasis of breast carcinoma are rare. Even if it is known that breast cancer can metastasize to many organ sites, metastasis to the uterus is uncommon and usually occurs during widespread metastatic disease, with only a limited number of such cases reported in the literature to date. Uterine metastases account for approximately 4% of genital tract metastases, with 47% of case involving as the primary site. We herein report the case of an 83-year-old female patient, who was diagnosed with endometrioid adenocarcinoma with metastases of infiltrating ductal carcinoma. Breast cancer is the most frequently diagnosed cancer globally and it is the leading cause of cancer-related death in women. Breast cancer screening programs and improved treatment of primary tumors have contributed significantly reducing overall mortality rates. Metastatic lesion are clearly secondary metastases of breast cancer in patients with disseminated disease, while other tumors can be confused with primary neoplasm. This group represents the tumors with high aggressiveness as these are less differentiated carcinomas, with a greater tendency to metastasize through the lymphatic and vascular structures.

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