An inclusive review on virology, transmission, and clinical management of COVID-19 resulting from SARS-CoV-2
DOI:
https://doi.org/10.30574/gscbps.2021.15.3.0149Keywords:
Corona Virus, SARS-CoV-2, Virology, Transmission, Clinical features diagnosis, VaccinationAbstract
Severe Acute Respiratory Syndrome Coronavirus-2 is the causative agent of Coronavirus Disease 2019 named by the World Health Organization (WHO) on 11th February 2020 and declared pandemic on March bears mild symptoms like fever, fatigue, dry cough to critical conditions like chronic respiratory disease leads to death. There are many misconceptions and vast internet information manipulating brains of the victimized society, which sow anxiety in people regarding this syndrome, and to provide adequate and accurate information literature reviews are must. This review article intends to deliver the current valuable information regarding the evolution, virology, and mode of transmission and epidemiology of SARS-CoV-2 along with the clinical management describing specific effective treatments, therapeutics, and vaccines through considering the clinical features of COVID-19. Several preventive measures, such as quarantine, self-isolation, and social distancing, are also elaborated. For the administration of this worldwide pandemic, the multifactorial assortment of endorsed examinations on each of these sections of COVID-19 inside this assessment empowers explanation and transparency on the existing eminence.
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Adhikari S, Meng S, Wu Y, Mao Y, Ye R, Wang Q, et al. Epidemiology, causes, clinical manifestation and diagnosis, prevention, and control of coronavirus disease (COVID-19) during the early outbreak: a scoping review. Infectious Diseases of Poverty. 2010; 9(1).
Contini C, Di Nuzzo M, Barp N, Bonazza A, De Giorgio R, Tognon M, Rubino S. The novel zoonotic COVID-19 pandemic: An expected global health concern. The Journal of Infection In Developing Countries. 2020; 14(03): 254-264.
Fu L, Wang B, Yuan T, Chen X, Ao Y, Fitzpatrick T. et al. Clinical characteristics of coronavirus disease 2019 (COVID-19) in China: A systematic review and meta-analysis. Journal of Infection. 2020; 80(6): 656-665.
Kakodkar P, Kaka N, Baig M. A Comprehensive Literature Review on the Clinical Presentation and Management of the Pandemic Coronavirus Disease 2019 (COVID-19). Cureus. 2020.
Long Q, Tang X, Shi Q, Li Q, Deng H, Yuan J, et al. Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections. Nature Medicine. 2020.
Qian G, Yang N, Ding F, Ma A, Wang Z, Shen Y, et al. Epidemiologic and clinical characteristics of 91 hospitalized patients with COVID-19 in Zhejiang, China: a retrospective, multi-centre case series. QJM: An International Journal of Medicine. 2020.
SHI Y. An overview of COVID-19. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology). 2020.
Singhal T. A Review of Coronavirus Disease-2019 (COVID-19). The Indian Journal of Pediatrics. 2020.
Sohrabi C, Alsafi Z, O'Neill N, Khan M, Kerwan A, Al-Jabir A, et al. orrigendum to “World Health Organization declares Global Emergency: A review of the 2019 Novel Coronavirus (COVID-19)” [Int. J. Surg. 76 (2020) 71–76]. International Journal of Surgery. 2020; 77: 217.
Wang X, Fang J, Zhu Y, Chen L, Ding F, Zhou R, et al. Clinical characteristics of non-critically ill patients with novel coronavirus infection (COVID-19) in a Fangcang Hospital. Clinical Microbiology and Infection. 2020.
A Study on Novel Corona Virus Disease (COVID-19) and its Preventive Measures. 2020; 14(4).
Alipio M. Epidemiology and Clinical Characteristics of 50 Death Cases with COVID-2019 in the Philippines: A Retrospective Review. SSRN Electronic Journal. 2020.
CDC Weekly C. The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) — China, 2020. China CDC Weekly. 2020; 2(8): 113-122.
Chen T, Dai Z, Mo P, Li X, Ma Z, Song S, et al. Clinical Characteristics and Outcomes of Older Patients with Coronavirus Disease 2019 (COVID-19) in Wuhan, China: A Single-Centered, Retrospective Study. The Journals of Gerontology: Series A. 2020.
Chen Y, Yang D, Cheng B, Chen J, Peng A, Yang C, et al. Clinical Characteristics and Outcomes of Patients With Diabetes and COVID-19 in Association With Glucose-Lowering Medication. Diabetes Care. 2020; 43(7): 1399-1407.
Li R, Tian J, Yang F, Lv L, Yu J, Sun G, et al. Clinical characteristics of 225 patients with COVID-19 in a tertiary Hospital near Wuhan, China. Journal of Clinical Virology. 2020; 127: 104363.
Li X, Wang L, Yan S, Yang F, Xiang L, Zhu J, et al. Clinical characteristics of 25 death cases with COVID-19: A retrospective review of medical records in a single medical centre, Wuhan, China. International Journal of Infectious Diseases. 2020; 94: 128-132.
Long‐quan L, Tian H, Yong‐qing W, Zheng‐ping W, Yuan L, Tao‐bi H, et al. Response to Char's comment: Comment on Li et al.: COVID‐19 patients' clinical characteristics, discharge rate, and fatality rate of meta‐analysis. Journal of Medical Virology. 2020.
Shalev N, Scherer M, LaSota E, Antoniou P, Yin M, Zucker J, Sobieszczyk M. Clinical Characteristics and Outcomes in People Living With Human Immunodeficiency Virus Hospitalized for Coronavirus Disease 2019. Clinical Infectious Diseases. 2020.
Shi Q, Zhang X, Jiang F, Zhang X, Hu N, Bimu C, et al. Clinical Characteristics and Risk Factors for Mortality of COVID-19 Patients With Diabetes in Wuhan, China: A Two-Center, Retrospective Study. Diabetes Care. 2020; 43(7): 1382-1391.
Wu J, Xia X, Liu H, Xia H, Huang W, Jia B, Peng F. Clinical Characteristics and Outcomes of Discharged COVID-19 Patients with Reoccurrence of SARS-CoV-2 RNA in a County Hospital of Western Chongqing, China. SSRN Electronic Journal. 2020.
Xiong F, Tang H, Liu L, Tu C, Tian J, Lei C, et al. Clinical Characteristics of and Medical Interventions for COVID-19 in Hemodialysis Patients in Wuhan, China. Journal of the American Society of Nephrology. 2020; 31(7): 1387-1397.
Yan Y, Yang Y, Wang F, Ren H, Zhang S, Shi X, et al. Clinical characteristics and outcomes of patients with severe COVID-19 with diabetes. BMJ Open Diabetes Research & Care. 2020; 8(1): e001343.
Yang J. Clinical Characteristics, Treatment, and Prognosis of 74 COVID-19 Patients from Cities outside Wuhan: A Descriptive Study. International Journal of Immunology and Immunotherapy. 2020; 7(1).
Yang P, Wang X, Liu P, Wei C, He B, Zheng J, Zhao D. Clinical characteristics and risk assessment of newborns born to mothers with COVID-19. Journal of Clinical Virology. 2020; 127: 104356.
Binnicker M. The emergence of a Novel Coronavirus Disease (COVID-19) and the Importance of Diagnostic Testing: Why Partnership between Clinical Laboratories, Public Health Agencies, and Industry Is Essential to Control the Outbreak. Clinical Chemistry. 2020; 66(5): 664-666.
FREE Download - Biotecnika Times 12th May 2020 Edition. Issuu. 2020.
Gao J, Tian Z, Yang X. Breakthrough: Chloroquine phosphate has shown apparent efficacy in the treatment of COVID-19 associated pneumonia in clinical studies. Bioscience Trends. 2020; 14(1): 72-73.
Gielen V, Johnston S, Edwards M. Azithromycin induces anti-viral responses in bronchial epithelial cells. 2020.
Hendaus M. Remdesivir in the treatment of coronavirus disease 2019 (COVID-19): a simplified summary. Journal of Biomolecular Structure and Dynamics. 2020; 1-6.
Hydroxychloroquine – An Antimalarial to Fight COVID-19? 2020; 16(06): 0716.
Information for Laboratories about Coronavirus (COVID-19). Centres for Disease Control and Prevention. 2020.
Kim G, Kim M, Ra S, Lee J, Bae S, Jung J, Kim S. Clinical characteristics of asymptomatic and symptomatic patients with mild COVID-19. Clinical Microbiology and Infection. 2020; 26(7): 948.e1-948.e3.
Loeffelholz M, Tang Y. Laboratory diagnosis of emerging human coronavirus infections – state of the art. Emerging Microbes & Infections. 2020; 9(1): 747-756.
Mboowa G. Current and emerging diagnostic tests available for the novel COVID-19 global pandemic. AAS Open Research. 2020; 3: 8.
Pascarella G, Strumia A, Piliego C, Bruno F, Del Buono R, Costa F, et al. COVID‐19 diagnosis and management: a comprehensive review. Journal of Internal Medicine. 2020.
Smolders E, te Brake L, Burger D. SARS-CoV-2 and HIV protease inhibitors: why lopinavir/ritonavir will not work for COVID-19 infection. Antiviral Therapy. 2020.
Tang Y, Schmitz J, Persing D, Stratton C. Laboratory Diagnosis of COVID-19: Current Issues and Challenges. Journal of Clinical Microbiology. 2020; 58(6).
Touma M. COVID-19: molecular diagnostics overview. Journal of Molecular Medicine. 2020.
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